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Our Research
Project 1: current NIH proposal: PPARδ/Ɣ
Funded NIH-R15, R43, R44.
Selective PPARδ/Ɣ agonist improves behavioral deficits and synaptic plasticity in a model of Alzheimer’s disease.
Project 2: LXR beta/PPAR
Selective LXR beta/PPAR alpha agonist improve behavioral deficits and synaptic plasticity in a model of Alzheimer’s Disease.
Project 3: RANBP9
RANBP9 inhibitor (NC-9) mitigates reduction in spine density and development of neurofibrillary tangle-mediated neurodegeneration in a model of Alzheimer’s disease.
Project 4: IS362
IS362, an FMO3 inhibitor, prevent TMAO-mediated synaptic deficits in models of Alzheimer’s disease and Diabetes type 2.
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